Sandra Oh often shut down the possibility of returning as Cristina Yang inGrey’s Anatomyin the past, but her latest comments about potentially revisiting the character make it worth pondering how could Cristina return to the medical drama. The third original intern to leave,Cristina’s exit had a massive impactnot because she joined the ranks of theGrey’s Anatomymain characters who were killed offbutbecause her departure deprived audiences of yet another iconic original character and her and Meredith’s glorious friendshiponscreen, after it had been such an important staple ofGrey’s Anatomyfor ten seasons.
As far as exits go onGrey’s Anatomy, Cristina’s was among the happiest, given how she left Seattle for a fantastic job that would have progressed the career she gave everything for and celebrated her friendship with Meredith in their last moments together.Grey’s Anatomybrought back many original characters in recent years, whether their exits involved their deaths or not, andCristina’s exit storyline made it easy to envision her return eventually, especially considering her strong bond with Grey Sloan Memorial.Sandra Oh’s comments about a potentialGrey’s Anatomyreturnmake Cristina’s visit to Seattle much likelier than before.

5Cristina Returns To Support Meredith In The Fight Of Her Career
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Meredith’s Alzheimer’s research that started inGrey’s Anatomyseason 18 brought her success as well as plenty of complications. This was true in the beginning when what Meredith theorized went against everything the scientific community had previously agreed on, but also more recently, in her struggle to get funds so that her and Amelia’s research could actually progress.
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It’s unclear where Meredith’s Alzheimer’s research will go, butif it were to cause Meredith to be in the fight of her career, Cristina could undoubtedly be there to support her. Cristina’s support would be necessary because she’s Meredith’s person, but her word could also hold power given her being a world-renowned medical professional. This could justify Cristina’s return as she has always been an essential part of Meredith’s life.

4Cristina Brings A Patient To Grey Sloan Memorial
Most Doctors Returned To Grey Sloan Memorial For A Patient
Cristina’s role as Chief Medical Officer at the prestigious Klausman Institute for Medical Research makes it unlikely she would need patient consults from halfway across the world. However,Cristina could nevertheless return to Grey Sloan Memorial to show a groundbreaking surgical technique to the new class of interns, out of allegianceto the hospital that made her the esteemed cardiothoracic surgeon she now is.
Cristina’s departure from Seattle and Grey Sloan Memorial came after being nominated for the Harper Avery only to lose it to somebody else, making a change of scenery necessary for her career to continue thriving.

While Cristina is one of the fewGrey’s Anatomycharacters still needing to return, plenty of those who did reappeared at Grey Sloan Memorial to let its residents witness a groundbreaking surgery. That was what delivered Addison’s return inGrey’s Anatomyseason 18 when she brought her patient Tovah Freedman to Grey Sloan ahead of her uterine transplant, but also Arizona Robbins’ in season 20, which led to the successful surgery in conjunction with Amelia Shepherd on Vida Madera.
3Cristina Returns To Stop A Threat To Grey Sloan Memorial’s Existence
Cristina Partially Owned Grey Sloan Once & Could Return If It Was Threatened
From tornadoes to wildfires, to a lack of teachers that risked the closure of its residency program, Grey Sloan Memorial had its fair share of threats to its existence to overcome. While management shakeups were more common inGrey’s Anatomy’s earliest years,Cristina already stepped up to save the hospital in the past when she became part-owner of Grey Sloan along with the Seattle Grace Five and Callie, making it possible she would again if Grey Sloan was in danger again.
[Cristina temporarily returning to save the hospital] would make her a hero among past and current Grey Sloan Memorial doctors.

Cristina’s temporary return to save Grey Sloan Memorial would make sense both for the emotional connection to the hospital and the fact visits from former doctors already attempted something similar, like Addison’s visit inGrey’s Anatomyseason 18 tried to do ahead of the hospital briefly losing its residency program. Such a return afterCristina’sGrey’s Anatomyexitwould make her a hero among past and current Grey Sloan Memorial doctors.
2Cristina Returns As A Patient
The Lives Of Most Grey Sloan Doctors Were Threatened At Least Once
One more unlikely but not impossible way Cristina could return toGrey’s Anatomyis as a patient.This would only work if Cristina remained for a longer arc in the medical drama, whether before or after the accident that turned her into a patient at Grey Sloan Memorial, but it could still be a reason for her to be seen again onGrey’s Anatomy.
HowGrey’s Anatomy’s Original Interns Left Grey Sloan Memorial
George
Died after he jumped in front of a bus in a bid to save a stranger.
Izzie
Left Seattle and Alex after losing her job at Seattle Grace.
Cristina
Left Grey Sloan Memorial to become the Chief Medical Officer of Klausman Institute for Medical Research in Switzerland.
Alex
Abruptly left Seattle to move to Kansas with Izzie and their children.
Meredith
Left Grey Sloan Memorial to work at the Fox Foundation to research Alzheimer’s.
Given how several amongGrey’s Anatomy’s doctors died or suffered life-threatening injuries at Grey Sloan, Cristina being there as a patient wouldn’t feel too far-fetched. At the same time, it would work better if the character whose life was in danger was a regular inGrey’s Anatomy, making it the least likely reason to bring Cristina back to Grey Sloan Memorial.

1Cristina Returns Because Meredith’s Life Is In Danger
Cristina Usually Was At Meredith’s Side When She Almost Died
Another reason that could bring Cristina back to Seattle has to do with Meredith again, as she still spends a lot of time there compared to any other doctor who left the show.Grey’s Anatomyseasons 15 and 16 proved thatCristina is still Meredith’s person offscreen, making it likely for Cristina to return if Meredith’s life was in danger.
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Every time Meredith risked her life, Cristina was at her bedside. While that wasn’t the case inGrey’s Anatomyseason 17 during the pandemic, on every other occasion Meredith could have seriously died, Cristina was there. With Meredith’s life not being threatened for a long time, if it was, it would be the perfect reason to bring Cristina Yang back toGrey’s Anatomy.
